Children and young adults with glomerular disease have unique risk factors for compromised bone health, but data on skeletal complications are lacking. We leveraged the PEDSnet pediatric health system population of more than 6.5 million children to compare incidence rates of adverse skeletal outcomes in patients with glomerular disease to a general pediatric reference cohort. Children and young adults with glomerular disease had greater risk of vertebral and hip/femur fractures, avascular necrosis/osteonecrosis, and slipped capital femoral epiphysis than those in the reference cohort. For fractures at any body site, girls with glomerular disease were at increased risk compared with peers in the general pediatric population, an effect that CKD does not appear to drive entirely.