Proton conducting solid oxide fuel cell (H-SOFC) is an emerging energy conversion device, with lower activation energy and higher energy utilization efficiency. However, the deficiency of highly active cathode materials still remains a major challenge for the development of H-SOFC. Therefore, in this work, K2NiF4-type cathode materials Pr2−xBaxNi0.6Cu0.4O4+δ(x = 0, 0.1, 0.2, 0.3), single-phase triple-conducting (e−/O2−/H+) oxides, are prepared for intermediate temperature H-SOFCs and exhibit good oxygen reduction reaction activity. The investigation demonstrates that doping Ba into Pr2−xBaxNi0.6Cu0.4O4+δcan increase its electrochemical performance through enhancing electrical conductivity, oxygen vacancy concentration and proton conductivity. EIS tests are carried at 750 °C and the minimum polarization impedances are obtained when x = 0.2, which are 0.068 Ω·cm2in air and 1.336 Ω·cm2in wet argon, respectively. The peak power density of the cell with Pr1.8Ba0.2Ni0.6Cu0.4O4+δcathode is 298 mW·cm−2at 750 °C in air with humidified hydrogen as fuel. Based on the above results, Ba-doped Pr2−xBaxNi0.6Cu0.4O4+δcan be a good candidate material for SOFC cathode applications.