In this study, water-based polyurethane coating with anti-graffiti property was prepared. The pot life and volatilization process of volatile matters of the coating were investigated. General properties of pencil hardness, flexibility, adhesion and impact resistance were tested. Along with the increase of anti-graffiti additive in coating formulation, the anti-graffiti performace of the resulted film was improved. Atomic force microscopy (AFM) was also carried out to determin the roughness of the coating surface.