Bioactive phenylpropanoids from Daphne feddei
- Resource Type
- article
- Authors
- Lu, Yanling; Li, Xuesen; Mu, Huaixue; Huang, Haitao; Li, Gan-Peng; Hu, Qiufen
- Source
- Journal of the Brazilian Chemical Society. April 2012 23(4)
- Subject
- Daphne feddei
phenylpropanoids
feddeiketones A-C
anti-HIV-1 activity
cytotoxic activity
- Language
- English
- ISSN
- 0103-5053
Investigation of acetone extract of the leaves and stems of Daphne feddei afforded three new phenylpropanoids, feddeiketones A-C (1-3), together with nine known phenylpropanoids (4-11). Their chemical structures were elucidated on the basis of spectroscopic methods. Compounds 1-3 were tested for their anti-HIV-1 activities and cytotoxicities against cancer cells. The results showed that compounds 1-3 have modest cytotoxic and anti-HIV-1 activities.