PURPOSE:: To report a technique to remove a dislocated ganciclovir implant in the vitreous cavity. METHODS:: Retrospective case series. Two patients with dislocated ganciclovir implants in the vitreous cavity. RESULTS:: A 6-mm pars plana incision was made; the soft tip was used to elevate the implant behind the intraocular lens and then 0.12-mm forceps were used to externalize the implant. The implant was successfully removed in both patients. CONCLUSION:: Removal of a dislocated ganciclovir implant with its encasing strut can be effectively retrieved using a bimanual approach.