OBJECTIVE: Meconium peritonitis (MP) is defined as sterile chemical peritonitis, resulting from intrauterine bowel perforation. MP is rare but has high morbidity and mortality in neonates. We aimed to review the treatment and clinical course of MP, and to find out the possible relationship between perinatal parameters and outcomes. METHODS: All patients diagnosed with MP between February 2006 and October 2016 were investigated retrospectively. MP was diagnosed with prenatal ultrasonography and the types of MP were identified intraoperatively. Findings of prenatal ultrasonography, gestational age, gender, birth weight, delivery type, APGAR score, clinical symptoms, causes of MP, mortality and morbidity, and hospital stay were analysed. RESULTS: Thirteen patients were antenatally diagnosed with MP. Median gestational age was 37 weeks. All patients were diagnosed using prenatal ultrasonography. Calcification was found in 13 patients, bowel dilatation in 8, fetal ascites in 7, polyhydramnios in 6, and pseudocyst in 3. Five were females and 8 were males. Median birth weight was 2,930 g. Symptoms of abdominal distension were reported in 10 patients, bilious vomiting in 2, pneumoperitoneum in 2, and no symptoms and signs of MP in 1. One patient recovered with conservative management and the other 12 patients required surgery. All patients who underwent surgery had underlying pathologic causes; jejunoileal atresia, ileal perforation and transverse colonic perforation. Two cases of mortality occurred. CONCLUSION: The mortality patients were haemodynamically unstable and had received preoperative pressor agents and ventilator care. More studies are needed to investigate the correlation between mortality and preoperative vital status.