OBJECTIVE: To compare the obstetric complications and perinatal outcomes of twin pregnancies conceived by In Vitro Fertilization and Embryo Transfer to twin pregnancies conceived naturally. METHODS: Maternal and neonatal data were reviewed for all twin pregnancies. All twin pregnancies (n=116) were divided into IVF twin pregnancyes group (n=43) and naturally conceived twin pregnancyes (n=72). The obstetric and perinatal outcomes were compared and analysed. Statistical analysis was performed using student's t-test, x2 test, and Fisher exact test. Statistical significance was defined as p<0.05. RESULTS: There were no significant differences in maternal age and gestational age between two groups but nulliparity was higher in IVF-ET twin group than naturally conceived twin group. Also no differences of obstetrics and perinatal outcomes were seen between two groups. CONCLUSION: Although twin pregnancies following IVF-ET are more likely to result in bad prognosis, in this study obstetric and perinatal outcomes are comparable to those of naturally conceived twin pregnancies.