The purpose of this study is to investigate the effect on changes in body composition and muscle function by applying a 12-week isotonic and isokinetic exercise program to elderly women with degenerative arthritis. The study subjects were 20 elderly women diagnosed with degenerative arthritis (10 in the isotonic exercise group and 10 in the isokinetic exercise group). Isotonic and isokinetic exercise recommended by the American Geriatrics Society for exercise arthritis for patients with degenerative arthritis (American Geriatrics Society Panel on Exercise & Osteoarthritis, 2001) Based on this, an exercise program was applied and implemented by supplementing it. Average difference between the initial experiment and 12 weeks after participation in the exercise program Two-way ANOVA (mixed) was performed for verification. First, the difference in body composition changes between exercise groups before and after exercise was not statistically significant in changes in body weight, muscle mass, body fat mass, body fat percentage, abdominal fat percentage (WHR), and basal metabolic rate (BMR). Second, changes in knee muscle function between exercise groups before and after exercise were significant in terms of time, group, time and group in Knee 60°/s, 180°/s Right, Left Flexion, and Extension (p<.05). In conclusion, It can be diversified into an isotonic exercise program that can be applied in the field without using special equipment or facilities, and can also be included in the field test of muscle strength evaluation during exercise instruction.