With sharp increases in vehicle, regulations for high fuel efficiency and emissions, triggered by concerns about environmental pollution and energy resources, are being strengthened. Development of eco-friendly materials for automobile has become key to survival for the automobile industry. In this study, center-pillar reinforcements were formed with TWB and a CR420/CFRP composite, which is used for parts in next-generation automobiles. The collision characteristics of the two materials were compared by conducting an experimental test and simulation. Before applying CFRP to CR420 steel, the tensile test, shear lap test, bending test, spring back test and formability were evaluated according to process parameters. From these many databases on experiment result, the production of next generation car component finally was successful in applying CR420/CFRP hybrid composite materials to car component. When the TWB was replaced with the next-generation CR420/CFRP composite material, the body weight of the car became lighter by approximately 44%, while impulse was improved by approximately 10.0%. The test specimens from CR420/CFRP hybrid composite materials were machined for each position, and their mechanical properties were investigated. The reasons for the differences in the mechanical properties according to position were ascertained by investigating the contact pressure using a simulation analysis. In regions where the contact pressure was lower than 0.5 MPa, the mechanical properties of the product deteriorated, indicating that the clearance at the side should be adjusted when designing the die to increase the contact pressure. Large quantities of voids greater than 50 lm in size were found in the specimens when the contact pressure was less than 0.5 MPa. The results obtained confirmed that these large quantities of voids caused the mechanical properties of the CFRP composite to deteriorate. After forming, collision tests were conducted to evaluate the fracture toughness by using experimental and theoretical methods. The collision properties of CR420/CFRP hybrid composites were measured and compared to study how much lighter the part is and how improved the fracture toughness is. It was confirmed that the physical properties of CR420 and CFRP were used in the collision test, and the simulation exhibited very similar results by comparing data obtained through the test and from references.