Purposes; The purposes of this study was to develop and apply an intervention program for the prevention of fractures in elderly women with osteopenia based on the health-promoting self-care system model by Simmons, and investigated its effects in order to help the subjects maintain and promote healthy lives. Methods; This study design was a nonequivalent control group pretest-posttest quasi-experimental design. The subjects included elderly women aged 65 or older with osteopenia, based on bone density measurements. They were assigned to an experiment group of 30 and a control group of 28. An intervention program for the prevention of fractures was administered in a total of 24 sessions with a 50 minute session twice per week for a period of 12 weeks. Data was collected from July to October, 2017, and the collected data was analyzed in descriptive statistics, Chi-square tests, and independent t-tests with the IBM SPSS 23.0/WIN. program. Measuring variables included prevention behaviors of osteoporotic fracture, body fat percentage, waist-hip ratio, basal metabolic rate, bone density, calcium diet intake, and osteoporosis self-efficacy. Results; After the application of the intervention program for the prevention of fractures, significant differences were found between the experiment and control group in acts to prevent a fracture, body fat percentage, waist-hip ratio, basal metabolic rate, calcium diet intake, and osteoporosis self-efficacy. There were no significant changes in bone density between the groups. Conclusion; The findings demonstrated that the intervention program for the prevention of fractures in elderly women with osteopenia encouraged them to practice better health behavior to prevent a fracture and was effective for maintaining and promoting their bone health. Based on these findings, the study proposes to expand its application to other individuals with weak bone health.