In this study, in order to develop catalysts for the selective isomerization of higher paraffin, the hydroisomerization reaction of n-dodecane was performed as a model reaction. MMZ-FER, MCM-41, MCM-48, and Ferrierite were used as supports for Pt/zeolite catalysts. Platinum was loaded on supports by various methods. The catalysts were characterized via X-ray powder diffraction, N2 adsorption, pridine-IR, and the temperature-programmed desorption of ammonia. Among the Pt/MMZ-FER catalysts, the Pt(IW 0.9)/MMZ-FER-0.67 showed the highest iso-dodecane yield at a reaction temperature of 326 ℃. Essentially, the amount of platinum loading did not affect significantly the iso-dodecane yield, which seemed to be due that platinum loading up to 1.2 wt% on MMZ-FER did not change the amount and the kind of acid sites. Pt/Al-MCM-41and Pt/Al-MCM-48 catalysts showed the highest iso-dodecane yield at a reaction temperature of 330 ℃, while n-dodecane hardly reacted over the catalyst without platinum. This means that platinum is necessary to isomerize n-dodecane. Iso-dodecane yield over Pt/FER catalyst synthesized by ALD method is higher than that over Pt/FER catalysts synthesized by IE or IW method, which is attribute to higher dispersion of Pt.