This study attempted to investigate the effects of beauty therapy on cognitive functions, depression and mood state among the elder woman through an 8-week test. For this, 39 people in Gyeonggi were selected and divided into experimental (20 people) and control (19 people) groups. The former participated in a beauty therapy program for 8 weeks. For data collection, pre-, intermediate and post-measurements and a questionnaire survey were conducted. The experiment was designed, using the 2x3 factorial design with repeated-measures on the second factor. The study results found the following: First, compared to the control group, cognitive score, time & place, orientation, memory registration, memory recall, language function and understanding & decision increased with statistical significance in the experimental group in which the elder woman participated in the beauty therapy program. Second, depression decreased with statistical significance in the experimental group, compared to the control group. Third, the experimental group revealed an increase in mood state with statistical significance, compared to the control group. The said results confirm that the elder woman participation in the beauty therapy program is a mediating factor that can maximize the positive effects of cognitive functions and psychological variables. Furthermore, it is anticipated that the study results will provide basic data in addition to the mediating effects of beauty therapy for the improvement of quality of life for the elder woman.