During his lifetime, OE Kenzaburo visited China six times and actively contributed to the promotion of SinoJapanese friendship and cultural exchanges. His death was an important event symbolizing a turning point in history and caused a great stir in China. The present paper focuses on the discussion of OE's relationship with China, and examines the legacy of OE's literature on Chinese literature and world literature through his six visits to China, his friendship with Chinese writers, and the reception of Lu Xun's works. OE studies in China have taken diverse forms, including intertextuality, acceptance of existentialism, perception of war, and criticism of the emperor system. What is worth noting is particularly the reception of and comparative studies on Chinese writers Lu Xun and Mogun, which include OE’s attachment to his hometown, the way OE depicts it from the perspective of animals and children, and the issue of marginality. The works of Lu Xun and Mogan provide a pathway to understanding OE. Put it in another way, in the present day, when people feel distant from Lu Xun's works, OE's works can break through the commercialized way of reading Lu Xun. Moreover, OE's works influenced not only Mogan but also Yan Lianke and Tie Guo, who focused on the universal theme of “despair and hope” by running through OE's works. From OE's literature, they acquired the logical basis of how to realize a true reconciliation between China and Japan.