We aimed to identify the differences between Korean and Chinese calligraphy therapy by examining the trends in Korean and Chinese calligraphy therapy and the effectiveness of the dependent variables. For the study, we initially screened 288 Korean articles and 429 Chinese articles, totaling 717 articles, published from January 1997 to December 2021. Using the PICOTS-SD standard, 6 Korean articles, 9 Chinese articles, and 15 total articles were identified as eligible for the study, and the collected data were analyzed using SPSS 26.0, a Microsoft EXCEL program. We found that there were significant differences in the number of follow-ups among publication formats, disease types, and main activity techniques (p<.05), and significant differences in the number of research and experimental participants in calligraphy therapy studies published in Korea and China and in the type of effect verification of the dependent variable (p<.01). In addition, based on the literature review and data analysis, it was found that there were differences in the qualities and experience of Korean and Chinese therapists and the intervention contents and methods of calligraphy therapy.