The purpose of this study was to analyze the published the literature of experimental study type regarding Physical therapy intervention for Charcot-Marie-Tooth (CMT) disease. We investigated by MEDLINE, Cochrane Library, EMBASE. Result show that number of published of literature of randomized controlled trial study type regarding Physical therapy intervention for CMT disease was one article. We confirmed that there was need to effort the establishment the system with systematic study and recognize the need of Physical therapy o intervention for improving of muscle strength of Dorsi-flexion and balance in the CMT disease.