This article aims to study how Chinese students have been influenced by mediating effects of social support while they had been self-disclosed, accultural-stressed to a various of college adjusting activities. In order to search their co-relationship, this author has collected data of 288 Chinese students studying in two universities at Jeollabuk-do and then tested it on the basis of structural equation model. To make sure the mediating effects of social support, this author has certified the partial mediating model and analyzed the full mediated model, eliminating one path of “self-disclosure→college activity adjustment” and the other path of “accultural-stress→college activity adjustment”, and finally compared two models and find that which model would be better. Consequently, this author has taken the partial mediating model because it has turned out more suitable. In the adopted model, he certified mediating effects of social support has shown that the social support has fully been mediating self-disclosure and college activity adjustment and partially been mediating accultural stress and college activity adjustment. This study has implied that in order to help Chinese students who study in Korea, make them exposed more to environment in which they could recognize social support for them, and by which they could reduce their accultural stress.