A new round of scientific and technological innovation promotes new infrastructure construction (hereinafter referred to as new infrastructure construction). New infrastructure supports digitization and intellectualization of all walks of life, realizes industrial intelligent operation and remote operation, and helps economic transformation and development. For the new infrastructure, Guangdong Province has a certain economic and industrial foundation, but at the same time, there are some problems, such as slow development, lack of innovation driving force, difficult to help industrial transformation and economic growth in a short time. Therefore, we should dredge financing channels, attract talents, guide the steady transformation of traditional infrastructure, promote the transformation and upgrading of manufacturing and service industries, and realize the high-quality economic development of Guangdong Province.