Big data has broad application prospects in the field of safety production. The paper cited big data in the safety production of a certain city in China as an example to analyze. Firstly, the concept of safety production big data were expounded. Then, the information status and business characteristics of big data in the safety production of a certain city in China were analyzed. Combining big data technology and safety production situations, the paper studied the technical route of big data analysis. According to the different business characteristics, the business data was analyzed. Finally, big data analysis was applied in the field of safety production, including the correlation analysis of big data, safety production composite index, and safety production multidimensional portrait. The results in this paper may contribute a lot to the daily monitoring of safe production and the accurate guidance of auxiliary supervision. With the help of big data analysis, some production accidents can be prevented, and the safety supervision efficiency can be greatly improved.