In order to realize the automatic detection of the effect of sample chip and improve the detection efficiency and accuracy, an automatic screening platform for sample chip is designed and developed. The platform has the advantages of high reliability, high degree of automation, simple operation and low cost. This paper describes the control process of the platform, the requirements of the automatic screening platform, the hardware and software design of the screening platform in detail. Finally, the experimental results show that the platform can effectively realize the automatic detection of sample chip quality, and improve the accuracy and efficiency of detection.