To solve the poor real-time problem of SIFT algorithm, the cooperative operation mechanism of multi-core algorithm on multi-thread mode is designed based on OpenMP software runtime. First, a collaboration mechanism between multiple processor cores is designed based on the multi-core operating framework. Then, a high-speed interaction method is designed for the data between different platforms based on the TCP/IP protocol. Finally, the experiment shows that this scheme can greatly make the processing speed up for highresolution image and effectively solves the real-time problem of the algorithm.