Acoustic detection of nanoparticle structural stability in physiological media after their laser irradiation
- Resource Type
- Conference
- Authors
- Zelepukin, I. V.; Popov, A. A.; Kabashin, A. V.; Deyev, S. M.; Zvyagin, A. V.
- Source
- 2020 International Conference Laser Optics (ICLO) Laser Optics (ICLO), 2020 International Conference. :1-1 Nov, 2020
- Subject
- Photonics and Electrooptics
Power, Energy and Industry Applications
Degradation
Radiation effects
Laser stability
Real-time systems
Physiology
Laser ablation
Structural engineering
nanoparticles
photoacoustics
laser ablation
degradation
- Language
- ISSN
- 2642-5580
Here we present a method of photoacoustic detection of nanoparticle degradation. To validate the method, we used biodegradable silicium nanoparticles, which can absorb light in the Uv-Vis region and generate acoustic waves in response. The photoacoustic method allows measuring kinetic of their degradation in real-time with high limit of detection up to a hundred ng of particles.