A Novel Glucose Controller using Insulin Sensitivity Modulation for Management of Type 1 Diabetes
- Resource Type
- Conference
- Authors
- Guemes, Amparo; Herrero, Pau; Georgiou, Pantelis
- Source
- 2019 IEEE International Symposium on Circuits and Systems (ISCAS) Circuits and Systems (ISCAS), 2019 IEEE International Symposium on. :1-5 May, 2019
- Subject
- Bioengineering
Components, Circuits, Devices and Systems
Power, Energy and Industry Applications
Signal Processing and Analysis
Insulin
Sugar
Sensitivity
Diabetes
Nervous system
Blood
Sociology
Bioelectronic medicine
bio-inspired artificial pancreas
glucose controller
insulin sensitivity
- Language
- ISSN
- 2158-1525
This paper introduces the use of bioelectronic medicine for glucose control in Type 1 diabetes. In particular, we present a new hybrid closed-loop glucose controller that regulates (i) the insulin and glucagon doses delivered using a pump and (ii) the value of insulin sensitivity of the patient, which would be modulated through electrical stimulation of the nervous system. The presented controller achieves improved glucose control with increased percentage of time of glucose levels within target and decreased hormonal delivery when compared with conventional glucose controllers. This work shows the potential of using bioelectronic modulation of insulin sensitivity for diabetes management.