In situ dynamic control of neurite growth by femtosecond laser ablation of substrate patterns
- Resource Type
- Conference
- Authors
- Okano, Kazunori; Liu, Lin-Li; Hosokawa, Yoichiroh; Masuhara, Hiroshi
- Source
- 2016 International Symposium on Micro-NanoMechatronics and Human Science (MHS) Micro-NanoMechatronics and Human Science (MHS), 2016 International Symposium on. :1-5 Nov, 2016
- Subject
- Bioengineering
Robotics and Control Systems
Laser ablation
Substrates
Neurons
Polymers
Laser theory
Surface emitting lasers
Chemical lasers
- Language
- ISSN
- 2474-3771
We are developing a methodology to construct a neuron network on a culture substrate for studying neuronal functions on signal processing and memory. Here we show a method to guide neurite growth on a substrate by using fem to second laser ablation of polymer layer. The laser was used to control the affinity of the surface to neurons and neurites. We succeeded in neurite growth with directionality.