An implementation for the simulation of cells on micro-post arrays
- Resource Type
- Conference
- Authors
- Truong, Duy T.; Bahls, Christian; Nebe, Barbara; van Rienen, Ursula
- Source
- 2016 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) Engineering in Medicine and Biology Society (EMBC), 2016 IEEE 38th Annual International Conference of the. :6138-6141 Aug, 2016
- Subject
- Bioengineering
Biological system modeling
Numerical models
Mathematical model
Adhesives
Strain
Tensile stress
- Language
- ISSN
- 1557-170X
1558-4615
The mechanical interaction between cells and their underlying substrates is important in understanding the processes that take place at an interface between biological tissue and the surface of implants. There have been numerous studies that examine these interactions both by experimental and numerical modeling. The bio-chemo-mechanical model for cell contractility by Deshpande et al. [1] has numerous applications and advantages. This work shows a way to implement this model in COMSOL MULTIPHYSICS® so it can be easily modified or extended. This will allow us in a next step to couple the differential system with additional external stimuli.