Predication the Suppressing Human Oral Cancer Cell Line by Curcumin through the Research of Fas Receptor
- Resource Type
- Conference
- Authors
- Chen, Po-Yuan; Wu, Yu-Chi; Cheng, Tzu-Hurng; Shih, Tzu-Ching; Tsai, Cing-Tsan; Wu, Chieh-Hsi; Hua, Tzu-Yu; Huang, Yen-Yu; Cheng, Chia-Hsing; Fan, Ming-Jen
- Source
- 2011 IEEE 11th International Conference on Bioinformatics and Bioengineering Bioinformatics and Bioengineering (BIBE), 2011 IEEE 11th International Conference on. :209-212 Oct, 2011
- Subject
- Bioengineering
Computing and Processing
Robotics and Control Systems
Signal Processing and Analysis
Communication, Networking and Broadcast Technologies
Components, Circuits, Devices and Systems
Tumors
Metastasis
Lymph nodes
Neck
Proteins
Pharmaceuticals
- Language
Curcumin is commonly applied as food coloring and seasoning but recent research show that curcumin is able to enhance the activation of Fas receptor to the cancer cell apoptosis through extrinsic pathway. Oral cancer results from the particular habit of chewing betel nuts that Taiwanese have. The additive in betel nuts (such as lime) is the main reason that increase the cancer rate of people chewing betel nuts and further increase the death rate gradually. The major treatments for oral cancer are still chemotherapy and surgery. This research expects to perform the computer simulation to calculate the activity of curcumin to oral cancer as medicine. The pharmaceutical activity are evaluate by the score from docking procedure perform by simulation program. We hope this experiment can be the evidence that curcumin can practically be used as medicine for oral cancer therapy in future.