HYPERHEALTH project is co-funded by Italian Space Agency (ASI) in the framework of the "PRISMA Scienza" program. The program supports R&D projects proposed by experts in hyperspectral remote sensing sector from national public research institutions to industries, also in the framework of international partnerships. The aim is designing, developing and testing innovative methods, techniques and algorithms for exploitation of hyperspectral data, with reliable perspectives as to engineering and pre-operational development, thus contributing to the improvement of socio-economic benefits of the end-user community. This paper outlines HYPERHEALTH main goals and activities.