Vascular transplantation is the main method for treating cardiovascular diseases. Autologous or xenogenous blood vessels exist in limited source, immunological rejection and no growth ability. Artificial blood vessel construction based on three-dimensional printing and tissue engineering technology provides new ideas for solving the above problems. To reconstruct the three-dimensional model of CT data of vascular tissue with MC algorithm as the core, and to analyze the reconstruction model with finite element method. Firstly, the medical image of human vascular tissue was extracted effectively by Mimics software, and the three-dimensional reconstruction and optimization of vascular tissue were completed. Four kinds of artificial vascular tissue models with different wall thickness and external diameter were designed. Then the stress of four groups of vascular tissue was analyzed by finite element software, and the suitable artificial vascular model for implantation was obtained.