Background: The Covid-19 pandemic has led to the largest disruption ineducation systems in human history. The use of online teaching increased daily,finally affecting more than 200 million students worldwide. The aim of thepresent study was to compare the prevalence of musculoskeletal pain in femalestudents during the Covid-19 pandemic with the pre-pandemic period.Methods: This cross-sectional study was performed in two stages: beforethe Covid-19 pandemic (October to December 2019) and during theCovid-19 pandemic (January to February 2020). The Nordic MusculoskeletalQuestionnaire (NMQ) was used to determine the musculoskeletal pain points.Data was analyzed using the t-test, McNemar test, and logistic regression inSPSS ver. 22, and a P