Effects of right ventricular remodeling in chronic thromboembolic pulmonary hypertension on the outcomes of balloon pulmonary angioplasty: a 2D-speckle tracking echocardiography study
- Resource Type
- article
- Authors
- Yaning Ma; Dichen Guo; Jianfeng Wang; Juanni Gong; Huimin Hu; Xinyuan Zhang; Yeqing Wang; Yuanhua Yang; Xiuzhang Lv; Yidan Li
- Source
- Respiratory Research, Vol 25, Iss 1, Pp 1-12 (2024)
- Subject
- Chronic thromboembolic pulmonary hypertension
Balloon pulmonary angioplasty
Right ventricular remodeling
Right ventricular free wall longitudinal strain
Predictor
Diseases of the respiratory system
RC705-779
- Language
- English
- ISSN
- 1465-993X
Abstract Background Balloon pulmonary angioplasty (BPA) improves the prognosis of chronic thromboembolic pulmonary hypertension (CTEPH). Right ventricle (RV) is an important predictor of prognosis in CTEPH patients. 2D-speckle tracking echocardiography (2D-STE) can evaluate RV function. This study aimed to evaluate the effectiveness of BPA in CTEPH patients and to assess the value of 2D-STE in predicting outcomes of BPA. Methods A total of 76 patients with CTEPH underwent 354 BPA sessions from January 2017 to October 2022. Responders were defined as those with mean pulmonary artery pressure (mPAP) ≤ 30 mmHg or those showing ≥ 30% decrease in pulmonary vascular resistance (PVR) after the last BPA session, compared to baseline. Logistic regression analysis was performed to identify predictors of BPA efficacy. Results BPA resulted in a significant decrease in mPAP (from 50.8 ± 10.4 mmHg to 35.5 ± 11.9 mmHg, p