Cardiac myosin activation in the treatment of congestive heart failure: New therapeutic options and review of literature
- Resource Type
- article
- Authors
- Arroj Ali; Ramy Abdelmaseih; Ravi Thakker; Mohammed Faluk; Syed Mustajab Hasan
- Source
- Heart Views, Vol 22, Iss 4, Pp 275-279 (2021)
- Subject
- heart failure
myosin
omecamtiv mecarbil
Diseases of the circulatory (Cardiovascular) system
RC666-701
- Language
- English
- ISSN
- 1995-705X
Congestive heart failure (HF) remains a major cause of cardiac-related morbidity and mortality, despite major therapeutic advancements. A newer class of medications has recently been developed which targets the root cause of HF, which is reduced myocardial contractility. This article aims to highlight the cardiac myosin activator class of drugs and the trials to date highlighting their effects on HF outcomes.