Cell division drives DNA methylation loss in late-replicating domains in primary human cells
- Resource Type
- article
- Authors
- Jamie L. Endicott; Paula A. Nolte; Hui Shen; Peter W. Laird
- Source
- Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
- Subject
- Science
- Language
- English
- ISSN
- 2041-1723
DNA methylation loss has been observed in aging tissues and cancers for decades. Researchers from Van Andel Institute have now provided experimental evidence that this process is directly driven by cell division.