目的:探讨MRI在胎儿颅脑病变诊断中的临床应用价值。方法:对78例超声怀疑颅脑病变的胎儿行MRI检查,并与产后2例及引产的38例胎儿的影像表现进行对照分析。结果:胼胝体发育不全32例,其中合并中线囊肿2例,并Dandy-Walker畸形6例,小脑发育不全4例,颅内广泛钙化1例;颅内出血15例,均为亚急性出血;颅内占位性病变13例,其中1例引产后病理证实为恶性畸胎瘤,囊肿12例(中线囊肿2例,鞍上池2例,环池1例,颅后窝7例);Dandy-Walker畸形12例,其中合并脑积水2例,脑裂畸形1例,脑回发育迟缓1例;无脑回畸形2例;Jourbert综合征2例;单侧巨脑症1例;颅缝早闭并指畸形(阿佩尔综合征)1例。结论:MRI在胎儿颅脑病变检查中具有重要作用,可以确认超声可疑诊断及完善补充、甚至更正超声诊断,为临床提供更全面可靠的影像资料。
Objective:To discuss the clinical prenatal diagnostic value of magnetic resonance imaging (MRI) in fetal cerebral abnormalities. Methods:78 gravidas with ultrasound (US) suspected fetal problems or diagnostic uncertainty underwent MRI. MRI imaging findings of the fetus were analyzed and compared with 2 cases postnatal brain MRI diagnosis and 38 cases in-duced labor MRI diagnosis or postmortem examination,assess the clinical value of MRI. Results:Agenesis of corpus callosum 32 cases,including midline cysts 2 cases,Dandy-Walker syndrome 6 cases,and cerebellar hypoplasia 4 cases,intracranial widespread calcification 1 case,intracranial hemorrhage 15 cases,subacute hemorrhage 15 cases,intracranial space occupying lesions 13 cas-es. Malignant teratoma 1 cases after induced labor and arachnoid cysts 12 cases (midline cysts 2 cases,suprasellar cistern 2 cases,cisterna ambiens 1 case,cisterna magna 7 case),Dandy-Walker 12 cases,including hydrocephaly 2 cases,schizencephaly 1 case,gyrus retardation 1 case,lissencephaly 2 cases,Jourbert syndrome 2 cases,unilateral megalencephaly 1 case,Apert syndrome 1 case. Conclusions:Magnetic resonance imaging techniques take part in the import role in diagnosis of fetal cerebral abnor-malities. It is a complementary and verification,it can even correct US diagnosis. MRI can provide more accurate and complete information for clinic.