[目的]探讨新生儿脐血IgE阳性与父母过敏史及出生情况的关系。[方法]对临产孕妇进行问卷调查及血清25-羟维生素D3检测,并采集脐血检测IgE,跟踪新生儿记录出生情况,分析脐血IgE值的相关因素。[结果]母亲有过敏性疾病史、新生儿出生时体重过大、男性及出生时窒息史等与脐血IgE阳性有相关性( OR=1.65、3.36、1.90和2.88,P<0.05)。[结论]母亲有过敏史是脐血IgE升高的危险因素,应做好母亲有过敏史婴儿的湿疹防治工作。
Objective To explore the relationship between neonatal cord blood IgE value and their parents allergies as well as birth status . [ Methods ] The pregnant women in labor were investigated by questionnaire and detected for blood 25-hydroxy vitamin D3 .The neonatal cord blood was collected for detection of IgE in childbirth , and the birth status was traced and recorded .Statistical analysis was done on the correlative factors of umbilical cord blood IgE . [ Results] The facts that mother had history of allergic diseases(OR=1.65), neonatal birth weight was too large (OR=3.36), baby was male (OR=1.90), and born with asphyxia (OR=2.88) were all associated with the positiveness of cord blood IgE (P<0.05). [Conclusion] The allergy history of mother is a risk factor for the rise of cord blood IgE, so measures for eczema prevention should be well taken for her baby .