Study on the relationship between microRNA and trophoblast cells and PE
- Resource Type
- Academic Journal
- Authors
- Wei-Hua Zu; Jing Liu; Yan-Lin Ma; Qi Li; Zhen Wang; Yuan-Hua Huang
- Source
- 海南医科大学学报(英文版) / Journal of Hainan Medical University. 27(2):61-64
- Subject
- miRNA
Preeclampsia
Trophoblast
Placenta
Target gene
- Language
- Chinese
- ISSN
- 1007-1237
Preeclampsia is a disease that occurs during pregnancy. Its pathogenesis is not clear. The delivery of placenta and fetus can effectively relieve symptoms. Trophoblast cells are the main cell components of placenta. The normal development of placenta depends on the normal differentiation, proliferation, migration and invasion of trophoblast cells. microRNA is a class of small non-coding RNA that are differentially expressed in PE patients and participate in the occurrence of PE by regulating the function of trophoblast cells. microRNA are expected to be early predictive markers of preeclampsia and provide new insights into the pathogenesis and treatment of PE.