This symposia will focus attention on the gap between technologies used in the lab and those used in the home. It addresses the question ‘how do we design technologies that will be used in home based practice for different types of impairments?’ Technologies are increasingly sophisticated and have many applications in supporting neuro-rehabilitation. Recent evidence from neurophysiological research and clinical studies has influenced rehabilitation interventions for the arm, providing valuable knowledge about how to apply technology-based therapy for people with neurological disorders, such as stroke and multiple sclerosis. However, home based use of such technologies remains limited. Do technologies need to be re-invented? The symposia will present some examples of novel home-based technologies, how they are underpinned by current understanding of neuroplasticity, users’ needs and expectations.