Physiological experiments in primates have identified a region of the midbrain tegmentum, the central mesencephalic reticular formation (cMRF), which plays a role in gaze control.1 Specifically, stimulation of this region produces horizontal saccades; recordings from this region reveal neurons with saccade-related activity; and chemical inactivation of this region produces contralateral head tilt and spontaneous saccades. More rostral regions of the midbrain reticular formation (MRF), just lateral to the interstitial nucleus of Cajal (InC), have neurons with vertical movement fields, and chemical inactivation of this region produces hypometric vertical saccades.2 In the macaque, there is an extensive overlap of tectoreticular terminals and reticulotectal cells in the region corresponding to the cMRF.3 The present study explored whether an area similar to the cMRF is present in the cat by analyzing the distribution of MRF neurons targeting the superior colliculus (SCol) and cervical spinal cord. These studies were carried out in eight adult cats under approved protocols adhering to the NIH guidelines. In the single-injection animals, 0.1-0.5 μl of a 10% BDA was injected into either the SCol or cervical cord. The SCol was approached dorsally, by aspirating the overlying cortex, while the cervical cord (C1) was approached through the foramen magnum. In the dual-tracer animals, both approaches were used to inject 5% Fast Blue into the SCol and 5% Fluoro-Gold into C1 (0.5 μl each). Standard perfusion and processing techniques were used.