Nuciferine attenuates acute ischemic stroke in a rat model: a metabolomic approach for the mechanistic study
- Resource Type
- Authors
- Chang Chen; Feipeng Duan; Yongyan Xie; Quan Wan; Haiyun Liu; Jinpeng Gong; Liping Huang; Zonghua Song
- Source
- Molecular omics. 18(8)
- Subject
- Glycerol
Aporphines
Glutathione Disulfide
Superoxide Dismutase
Tumor Necrosis Factor-alpha
Lysine
Fatty Acids
Interleukin-1beta
Glycine
Catalase
Biochemistry
Glutathione
Antioxidants
Choline
Rats
Malondialdehyde
Genetics
Serine
Animals
Tyrosine
Histidine
Molecular Biology
Ischemic Stroke
Peroxidase
- Language
- ISSN
- 2515-4184
Nuciferine is a promise therapeutic candidate for ischemic stroke. 1H NMR metabolomics was conducted in this study to further elucidate its pharmacological mechanism, which is helpful to be used as a potential treatment for stroke clinically.