Characterisation of 2-HP-β-cyclodextrin-PLGA nanoparticle complexes for potential use as ocular drug delivery vehicles
- Resource Type
- Authors
- Lizhong Liu; Zhenjie Mo; Junfeng Ban; Yan Zhang; Qing Liu; Zhufen Lu; Kangyu Zheng; Yuqin Wen; Fan Li; Yifeng Wen; Qingchun Xie; Yanzhong Chen; Fohua Chen
- Source
- Artificial Cells, Nanomedicine, and Biotechnology. 47:4097-4108
- Subject
- Triamcinolone acetonide
Biomedical Engineering
Pharmaceutical Science
Medicine (miscellaneous)
Nanoparticle
02 engineering and technology
Eye
Cornea
Plga nanoparticles
03 medical and health sciences
chemistry.chemical_compound
2-Hydroxypropyl-beta-cyclodextrin
0302 clinical medicine
Polylactic Acid-Polyglycolic Acid Copolymer
medicine
Animals
chemistry.chemical_classification
Drug Carriers
Cyclodextrin
Aqueous humour
General Medicine
021001 nanoscience & nanotechnology
Drug Liberation
PLGA
chemistry
030220 oncology & carcinogenesis
Drug delivery
Nanoparticles
Rabbits
0210 nano-technology
Biotechnology
Nuclear chemistry
medicine.drug
- Language
- ISSN
- 2169-141X
2169-1401
Aim: 2-HP-β-cyclodextrin-PLGA nanoparticle complexes were prepared to enhance the aqueous humour delivery of Triamcinolone acetonide.Materials & methods: Drug-loaded 2-HP-β-CD/PLGA nanoparticle com...