Additional file 1: Table S1. Hepatic differential lipophilic metabolites with good matches between the treated group (50 mg/kg) and the control group. Table S2. Serum differential lipophilic metabolites with good matches between the treated group (50 mg/kg) and the control group. Table S3. Feces differential lipophilic metabolites with good matches between the treated group (50 mg/kg) and the control group. Table S4. Differential phosphatidylcholines (PCs) in liver, serum and feces between the treated group (50 mg/kg) and the control group. Figure S1. KEGG pathway map of glycerophospholipid metabolism. Figure S2. Score scatter plot for principal component analysis (PCA) model with total lipophilic metabolites and quality control (QC) samples. Figure S3. Permutation test of orthogonal projections to latent structures-discriminant analysis (OPLS-DA) model.