Detection of Non-Hodgkin Lymphoma Within Ovarian Tissue
- Resource Type
- Article
- Authors
- Vicenti, R; Magnani, V; Del Forno, S; De Meis, L; Caprara, G; Raimondo, D; Paradisi, R; Fabbri, R; Seracchioli, R
- Source
- Journal of Adolescent and Young Adult Oncology. 12:280-283
- Subject
- Adult
Cryopreservation
03 medical and health sciences
0302 clinical medicine
Cysts
Lymphoma, Non-Hodgkin
Ovary
Humans
non-Hodgkin lymphoma
cryopreservation
autotransplantation
histological assessment
Female
3. Good health
- Language
- ISSN
- 2156-535X
2156-5333
This case report describes the detection of non-Hodgkin lymphoma (NHL) within ovarian tissue after cryopreservation. The 27-year-old woman presented no gynecological symptoms such as pelvic pain or abnormal uterine bleeding. During laparoscopy for ovarian tissue cryopreservation, the ovaries appeared markedly modified and some solid content cysts were highlighted. Microscopically the cysts revealed the presence of lymphoid infiltrate, whereas the histological assessment of some fragments of the ovarian cortical tissue revealed no evidence of pathological lymphoid infiltration. This case report describes the presence of pathological lymphoid infiltration in ovarian cysts but not in the cortical tissue of a young woman with secondary NHL. Despite the absence of the positivity in cortical tissue it was recommended to avoid the cryopreserved ovarian tissue transplantation to reduce the risk of reseeding of the malignancy in the woman.