Radiolabeled Thioflavin-T Derivative PET Imaging for the Assessment of Cardiac Amyloidosis
- Resource Type
- Authors
- Kevin Emery Boczar; Gary Small; Anahita Tavoosi; Terrence D. Ruddy
- Source
- Current Cardiology Reports. 24:1883-1891
- Subject
- Cardiology and Cardiovascular Medicine
- Language
- ISSN
- 1534-3170
1523-3782
Cardiac amyloidosis (CA) is an often under-recognized cause of heart failure with preserved ejection fraction. The goal of the current paper was to review imaging modalities available for detecting cardiac amyloidosis. We wished to determine what modalities are available for the diagnosis of cardiac amyloidosis and what modalities could be utilized in the future.Early and delayed planar imaging of the chest currently plays a central role in the workup and diagnosis of CA. However, novel positron emission tomography (PET) tracers could play a large role in CA imaging in the future. There is an increasing body of literature supporting the use of targeted amyloid-binding PET radiotracers such as