Huge Pulmonary Arteriovenous Malformation, Venous Thromboembolism and Anticoagulation Treatment in a Patient with Hereditary Hemorrhagic Telangiectasia
- Resource Type
- Authors
- Natalia Causada Calo; Ezequiel Levy Yeyati; Marcelo M. Serra; Diego Andresik; Martin Rabellino; Teresa Garcia-Botta; Bruno L. Ferreyro; Oscar Peralta; Ricardo García-Mónaco
- Source
- Internal Medicine. 54:2745-2748
- Subject
- medicine.medical_specialty
Anticoagulation Treatment
Hypoxemia
Arteriovenous Malformations
Multidetector Computed Tomography
Internal Medicine
medicine
Humans
Right upper lobe
Hypoxia
Pulmonary arteriovenous malformation
Telangiectasia
Aged
Cyanosis
business.industry
Incidence
Anticoagulants
Venous Thromboembolism
General Medicine
medicine.disease
Embolization, Therapeutic
Pulmonary embolism
Venous thrombosis
Treatment Outcome
Female
Telangiectasia, Hereditary Hemorrhagic
Radiology
medicine.symptom
business
Venous thromboembolism
- Language
- ISSN
- 1349-7235
0918-2918
Hereditary hemorrhagic telangiectasia (HHT) usually presents in association with pulmonary arteriovenous malformations (PAVMs). In addition, the incidence of venous thromboembolism tends to be increased in these patients. A 74-year-old female with HHT presented with cyanosis and hypoxemia. Contrast-enhanced multislice computed tomography (MSCT) revealed two left PAVMs and one in the right upper lobe. Both left PAVMs were treated with embolotherapy. Follow-up MSCT revealed an incidental pulmonary embolism in the right pulmonary branches. Deep venous thrombosis was confirmed and anticoagulation was initiated. Follow-up MSCT revealed the resolution of thromboembolism. Finally, embolotherapy was performed. This case illustrates the chronic adaptation to hypoxemia and adds further evidence to the relative safety of anticoagulation treatment in these patients.