Dual-Engine Powered Paper Photoelectrochemical Platform Based on 3D DNA Nanomachine-Mediated CRISPR/Cas12a for Detection of Multiple miRNAs
- Resource Type
- Authors
- Chuan Huang; Lu Zhang; Yuanna Zhu; Zuhao Zhang; Yunqing Liu; Chao Liu; Shenguang Ge; Jinghua Yu
- Source
- Analytical chemistry. 94(22)
- Subject
- MicroRNAs
Quantum Dots
Biosensing Techniques
DNA
Electrochemical Techniques
CRISPR-Cas Systems
Analytical Chemistry
- Language
- ISSN
- 1520-6882
This work proposed a novel double-engine powered paper photoelectrochemical (PEC) biosensor based on an anode-cathode cooperative amplification strategy and various signal enhancement mechanisms, which realized the monitoring of multiple miRNAs (such as miRNA-141 and miRNA-21). Specifically, C