Aspartate aminotransferase to platelet ratio index (APRI) score: is it useful in patients with intrahepatic cholestasis of pregnancy?
- Resource Type
- Authors
- Ömer Gökhan Eyisoy; Ümit Taşdemir; Mucize Eriç Özdemir; Seden Eyisoy; Özge Kahramanoğlu; Aydın Öçal; Oya Demirci
- Source
- The journal of maternal-fetalneonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians. 35(25)
- Subject
- Pregnancy Complications
Liver Cirrhosis
ROC Curve
Pregnancy
Pediatrics, Perinatology and Child Health
Infant, Newborn
Obstetrics and Gynecology
Humans
Female
Cholestasis, Intrahepatic
Aspartate Aminotransferases
Retrospective Studies
- Language
- ISSN
- 1476-4954
It is aimed to evaluate the efficacy of using aspartate aminotransferase (AST)/platelet count ratio [AST to platelet ratio index (APRI) score] in ICP patients.This study was carried out including 101 patients diagnosed with ICP (72 patients with mild ICP and 29 patients with severe ICP). Laboratory tests and neonatal outcomes of both groups were analyzed retrospectively. APRI scores were compared between the two groups. Receiver operating characteristic (ROC) analysis was used to evaluate the performance of the APRI score in determining the severity of ICP and the prediction of adverse neonatal outcomes.Patients with severe ICP had higher APRI scores than patients with mild ICP (The APRI score may not be the perfect differentiating method for the severity of ICP but it may help the clinician working with limited resources.