One-Pot Arylative Benzannulation of 2-Carbonyl-3-propargyl Indoles with Boronic Acids Leading to Arylated Carbazoles
- Resource Type
- Authors
- Chada Raji Reddy; Muppidi Subbarao; Ramachandra Reddy Donthiri; Puppala Sathish; Ejjirotu Srinivasu
- Source
- The Journal of organic chemistry. 86(1)
- Subject
- Annulation
chemistry.chemical_compound
chemistry
Organic Chemistry
Propargyl
Organic chemistry
chemistry.chemical_element
Triflic acid
Catalysis
Palladium
- Language
- ISSN
- 1520-6904
Arylative annulation of 2-carbonyl-3-propargyl indoles with boronic acids under sequential palladium/triflic acid catalysis is described. The present strategy to provide di- and triaryl carbazoles in one pot involves benzannulation through difunctionalization of alkynes. The strategy showed a good substrate scope with respect to boronic acids as well as 2-carbonyl-3-propargyl indoles to afford the corresponding carbazoles in decent yields.