Serum tissue inhibitor of MMP-1 levels at any moment of the first week of spontaneous intracerebral hemorrhage may predict early mortality
- Resource Type
- Authors
- Jordi Solé-Violán; Leonardo Lorente; María M. Martín; Antonia Pérez-Cejas; Alejandro Jiménez; Agustín F. González-Rivero; Mónica Argueso; Rafael Sabatel; Juan J. Cáceres; Luis Ramos-Gómez
- Source
- Biomarkers in medicine. 15(14)
- Subject
- Male
medicine.medical_specialty
Clinical Biochemistry
Matrix metalloproteinase
Gastroenterology
Internal medicine
Drug Discovery
Area under curve
medicine
Humans
Glasgow Coma Scale
Spontaneous intracerebral hemorrhage
Mortality prediction
Prospective Studies
Aged
Cerebral Hemorrhage
Tissue Inhibitor of Metalloproteinase-1
business.industry
Biochemistry (medical)
Serum concentration
Middle Aged
Matrix Metalloproteinase 9
Female
Matrix Metalloproteinase 1
business
Biomarkers
- Language
- ISSN
- 1752-0371
Aim: To determine whether serum levels of MMP-9 and tissue inhibitor of matrix metalloproteinases (TIMP)-1 during the first week after spontaneous intracerebral hemorrhage (SIH) could be used for mortality prediction. Materials & methods: We included 117 patients with severe supratentorial SIH (defined as Glasgow Coma Scale