Additional file 1: Figure S1. Identification of mice of different genotypes. A PCR analysis of the expression of Flox-Hdac3 and Cre gene in LysmCreHdac3f/f, LysmCreHdac3f/w, LysmCre, Hdac3f/f, Hdac3f/w and WT mice. B Western blot analysis of HDAC3 of BMDMs from LysmCre and LysmCreHdac3f/f mice. Figure S2. HDAC3 deficient macrophages have elevated expression of Ctsd. A PCR analysis of Ctsd in Vector, Hdac1−/−, Hdac2−/−, Hdac3−/−, Hdac8−/− RAW264.7 cells. B-C Western blot analysis of CTSD in Vector, Hdac1−/−, Hdac2−/−, Hdac3−/−, Hdac8−/− RAW264.7 cells. Data are representative of three independent experiments and showed as mean ± SEM. *P