Additional file 1: Figure S1: Study design and Identification of CACNA1G gene based on the pharmaco-epigenomic method. Figure S2: Methylation levels of (A) ADAMTS1, (B) BNC1, (C) CACNA1G genes in the Cancer Genome Atlas [Díez-Villanueva A, Mallona I, Peinado MA. Wanderer, an interactive viewer to explore DNA methylation and gene expression data in human cancer. Epigenetics Chromatin 2015;8:22. https://doi.org/10.1186/s13072-015-0014-8 ].