Complementary and integrative health strategies are increasingly used by the public to treat a variety of health concerns and to improve wellness. Many individuals with mental health diagnoses, including post-traumatic stress disorder (PTSD), have incorporated a group of complementary and integrative health strategies known as mind and body practices in their health care regimen. These practices include meditation, acupuncture, deep breathing and relaxation techniques, massage therapy, yoga, and biofeedback/neurofeedback. Thus far, the literature on the efficacy of mind and body interventions for PTSD is limited and better studies are needed to test both efficacy and effectiveness. This chapter presents information on the use of mind and body practices for PTSD, referring primarily to systematic reviews and meta-analyses. The National Center for Complementary and Integrative Health recently released its fourth strategic plan, Exploring the Science of Complementary and Integrative Health, which emphasizes the development of a strong evidence base in complementary and integrative heath research.