肺鳞癌的基因组测序和基因编辑
- Resource Type
- Authors
- xie, guoyun
- Source
- Subject
- Monoisolate
Genome sequencing
- Language
- English
The study sought to explore novel genetic aberration driving squamous cell lung carcinoma (LUSC). The whole exome (WES), whole genome (WGS) and target region (TS) sequencings and CRISPR-Cas9 genome editing techniques were integrated to explore and validate novel targeting candidates from LUSC primary tumors and corresponding patient-derived xenografts (PDXs).